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A highly personalized experience provided by a team of academic plastic surgeons.

Mark Sisco, MD

Faculty Appointments
Clinical Appointments
Education
Graduate Medical Education
Postdoctoral Research Training
Medical Licensure
Committee Service
Awards, Honors, Distinctions
Professional Society Memberships
Professional and Scientific Service
Research Grants/contracts
Original, peer-reviewed research articles
Reviews, Chapters, Books
Case reports, Technical notes, Letters
Abstracts

Division of Plastic and Reconstructive Surgery
NorthShore University HealthSystem
501 Skokie Boulevard
Northbrook, IL 60062
Office: 847.504.2300
Fax: 847.504.2305

 

FACULTY APPOINTMENTS
8/2009-present Clinical Assistant Professor, Department of Surgery
University of Chicago, Pritzker School of Medicine, Chicago, IL
7/2008-6/2009 Clinical Instructor, Department of Surgery
Memorial Sloan-Kettering Cancer Center, New York, NY
7/2007-6/2008 Clinical Instructor, Department of Surgery
Northwestern University Feinberg School of Medicine, Chicago, IL
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CLINICAL APPOINTMENTS
7/2009-present Attending Physician, Division of Plastic Surgery, Department of Surgery
NorthShore University HealthSystem, Evanston, IL
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EDUCATION
6/2000 Doctor of Medicine, Northwestern University Feinberg School of Medicine
5/1996 Bachelor of Arts, Columbia College, Columbia University
Concentration in Art History
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GRADUATE MEDICAL EDUCATION
7/2008-6/2009 Clinical Fellow in Reconstructive Microsurgery, Division of Plastic Surgery
Memorial Sloan-Kettering Cancer Center
Program Director: Dr. Peter Cordeiro
7/2007-6/2008 Administrative Chief Resident, Division of Plastic and Reconstructive Surgery
McGaw Medical Center of Northwestern University
Program Director: Dr. Gregory A. Dumanian
7/2005-6/2007 Resident, Division of Plastic and Reconstructive Surgery
McGaw Medical Center of Northwestern University
Program Director: Dr. Gregory A. Dumanian
7/2001-6/2004 Intern and Resident, Department of Surgery
McGaw Medical Center of Northwestern University
Program Director: Dr. Richard H. Bell
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POSTDOCTORAL RESEARCH TRAINING
7/2004-6/2005 Research Resident, Wound Healing Research Laboratory
Division of Plastic and Reconstructive Surgery
Northwestern University Feinberg School of Medicine
Studied cutaneous ischemia-reperfusion injury and hypertrophic scarring
Mentor: Dr. Thomas A. Mustoe
1/2000-6/2001 Research Fellow, Wound Healing Research Laboratory
Division of Plastic and Reconstructive Surgery
Northwestern University Feinberg School of Medicine
Explored wound-healing response to aging and ischemia
Mentor: Dr. Thomas A. Mustoe
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MEDICAL LICENSURE

Illinois license
New York license
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COMMITTEE SERVICE
1996-2000 Executive Curriculum Committee
Northwestern University Feinberg School of Medicine
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AWARDS, HONORS, DISTINCTIONS
1996 Columbia College, cum laude in Art History
2000 Alpha Omega Alpha Honor Society
2008 Edelstone-Bendix Chief Resident Research Prize, Northwestern University
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PROFESSIONAL SOCIETY MEMBERSHIPS

Active Member, Association for Academic Surgery
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PROFESSIONAL and SCIENTIFIC SERVICE

Peer Reviewer, Wound Repair and Regeneration
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RESEARCH GRANTS/CONTRACTS
2000-2001 Buehler Center on Aging, Northwestern University
“A Gene Array Assay of Wound Healing in an Aged Ischemic Model.”
Co-Investigator, $13,000
2000-2001 American Society for Aesthetic Plastic Surgery
“Microarray Gene Expression Analysis of Human Scarring.”
Co-Investigator, $8,000
1997 Northwestern University Medical School Summer Research Fellowship
“Arterial Base Deficit as a Predictor of Resuscitation in Septic Patients.”
Student Investigator, $2,500
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SCHOLARLY BIBLIOGRAPHY

Original, peer-reviewed research articles

  1. Mogford JE, Sisco M, Bonomo SR, Robinson AM, and Mustoe TA: “Impact of Aging on Gene Expression in a Rat Model of Ischemic Cutaneous Wound Healing.” J Surg Res. 2004;118(2):190-6. (co-first author)
  2. Sisco M, Liu WR, Kryger ZB, and Mustoe TA: “Reduced Up-Regulation of Cytoprotective Genes in Rat Cutaneous Tissue During the Second Cycle of Ischemia-Reperfusion.” Wound Repair Regen. 2007;15(2):203-12.
  3. Kryger ZB, Sisco M, Roy N, Lu L, Rosenberg D, and Mustoe TA: “The Temporal Expression of the TGF-beta Pathway in the Rabbit Ear Model of Wound Healing and Scarring.” J Am Coll Surg. 2007;205(1):78-88.
  4. Sisco M, Chao JD, Kim I, Mogford JE, Mayadas TN, and Mustoe TA: “Delayed Wound Healing in Mac-1–Deficient Mice Is Associated with Normal Monocyte Recruitment.” Wound Repair Regen. 2007;15(4):566-71.
  5. Brown RJ, Lee MJ, Sisco M, Kim JY, Roy N, and Mustoe TA: “High-Dose Ultraviolet Light Exposure Reduces Scar Hypertrophy in a Rabbit Ear Model.” Plast Recon Surg. 2008;121(4):1165-72.
  6. Sisco M, Kryger ZB, O’Shaughnessy KD, Kim PS, Schultz GS, Ding XZ, Roy NK, Dean NM, and Mustoe TA: “Antisense Inhibition of Connective Tissue Growth Factor (CTGF/CCN2) mRNA Limits Hypertrophic Scarring Without Affecting Wound Healing in Vivo.” Wound Repair Regen. 2008;16(5):661-73.
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Reviews, Chapters, Books

  1. Sisco M and Mustoe TA: “Animal Models of Ischemic Wound Healing. Toward an Approximation of Human Chronic Cutaneous Ulcers in the Rabbit and Rat.” Methods Mol Med. 2003;78:55-65.
  2. Kryger ZB and Sisco M, Eds.: Practical Plastic Surgery. Austin: Landes Bioscience, 2007.
  3. Sisco M and Bauer BS: “Craniofacial Syndromes and Sequences.” In Bentz ML, Bauer BS, and Zucker R, Eds.: Principles and Practice of Pediatric Plastic Surgery. St. Louis: Quality Medical Publishing, 2007.
  4. Sisco M and Disa JJ: “Mandible Reconstruction.” In Marsh J and Perlyn C, Eds.: Decision Making in Plastic Surgery. St. Louis: Quality Medical Publishing, In Press.
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Case reports, Technical notes, Discussions, Letters

  1. Sisco M and Dumanian GA: “A Simple Technique to Anchor Prosthetic Mesh to Bone.” Plast Recon Surg. 2005;116(7):2059-60.
  2. Sisco M and Dumanian GA: Invited Discussion of “Salvaging Limbs in Cases of Severe Purpura Fulminans: Advantages of Free Flaps.” Plast Recon Surg. 2006;118(3):686-7.
  3. Erickson BA, Dumanian GA, Sisco M, Jang TL, Halverson AL, and Gonzalez CM: “Rectourethral Fistula Associated with Two Short Segment Urethral Strictures in the Anterior and Posterior Urethra: Single-Stage Reconstruction Using Buccal Mucosa and a Radial Forearm Fasciocutaneous Free Flap.” Urology. 2006;67(1):195-8.
  4. Sisco M and Dumanian GA: “Anterior Interosseous Nerve Syndrome Following Shoulder Arthroscopy. A Report of Three Cases.” J Bone Joint Surg Am. 2007;89(2):392-5.
  5. Sisco M and Dumanian GA: “The Implantable Venous Doppler for Perforator Flap Monitoring: Report of a False-Negative Signal.” Plast Recon Surg. 2008;121(4):223e-4e.
  6. Sisco M and Disa JJ: Invited Discussion of “NPWT I: The Paradox of Negative Pressure Wound Therapy.” Plast Recon Surg. 2009; 123(2):599-600.
  7. MacIver RH, Sundaresan S, DeHoyos AL, Sisco M, and Blum MG: “Mucosal Tube Technique for Creation of Esophageal Anastomosis after Esophagectomy.” Ann Thorac Surg. 2009;87(6):1703-7.
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Abstracts

  1. Zhao Y, Sisco M, Mogford J, and Mustoe TA: “Effects of Ischemia on a Model of Non-Contractile Cutaneous Wound Healing in the Rat.” Oral Presentation. Wound Healing Society Annual Meeting, Toronto, June 2000.
  2. Sisco M, Mogford JE, Robinson AM, Zhao Y, and Mustoe TA: “Gene Array Analysis of the Impact of Aging and Ischemia on Wound Healing in Rats.” Oral Presentation. Wound Healing Society Annual Meeting, Albuquerque, NM, June 2001.
  3. Sisco M, Chao J, Kim I, Mayadas-Norton T, Mogford JE, and Mustoe TA: “Delayed Wound Healing in Mac-1 (CD11b/CD18) Integrin Knockout Mice.” Oral Presentation. Wound Healing Society Annual Meeting, Albuquerque, NM, June 2001.
  4. Cross KJ, Sisco M, Mogford J, and Mustoe TA. “A Novel Ischemic Wound Healing Model in the Rat: a Bipedicled Back Flap with Internal Controls.” Oral Presentation. Wound Healing Society Annual Meeting, June 2002.
  5. Kryger ZB, Sisco M, Roy NK, and Mustoe TA: “The Temporal mRNA Expression of the TGF-Beta Pathway in the Rabbit Ear Model of Hypertrophic Scarring.” Poster Presentation. Plastic Surgery Research Council, Toronto, May 2005.
  6. Kryger ZB, Sisco M, Lu WR, and Mustoe TA: “Attenuated Stress- and Hypoxia-Driven Gene Expression in a Rat Model of Repetitive Cutaneous Ischemia-Reperfusion Injury.” Oral Presentation. American College of Surgeons Clinical Congress, San Francisco, October 2005.
  7. Sisco M, Kryger ZB, Jia SX, Schultz GS, Dean NM, and Mustoe TA: “Antisense Oligonucleotides Against Transforming Growth Factor-Beta Delay Wound Healing in a Rabbit Ear Model.” Oral Presentation. American College of Surgeons Clinical Congress, San Francisco, October 2005.
  8. Sisco M, Kryger ZB, Schultz GS, Roy NK, Dean N, and Mustoe TA: “Antisense Inhibition of Connective Tissue Growth Factor Limits Hypertrophic Scarring In Vivo: Evidence for a Specific Target to Reduce Fibrosis.” Oral Presentation. Plastic Surgery Research Council, Dana Point, CA, May 2006.
  9. Sisco M and Dumanian GA: “The Oblique Rectus Abdominis Myocutaeous Flap for Vaginal Reconstruction.” Oral Presentation. Midwestern Association of Plastic Surgeons, Chicago, May 2007.
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Instructional Courses

  1. Chicago Rhinoplasty Symposium. NorthShore University HealthSystem. Evanston, IL. May 2010.
  2. Incorporating Nipple Sparing Mastectomy (NSM) Into Your Practice. American Society of Plastic Surgeons Annual Meeting. Toronto. October 2010.
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